Nothing is confirmed in terms of story, but Matthew Vaughn did talk about a couple of interesting ideas for the sequel:
"I've got some ideas for the opening for the next film. I thought it would be fun to open with the Kennedy Assassination, and we reveal that the magic bullet was controlled by Magneto. That would explain the physics of it, and we see that he's pissed off because Kennedy took all the credit for saving the world and mutants weren't even mentioned. And we could go from there, and I've got some fun ideas about what other mutants to bring in. I don't want to tempt fate, though. If the film's a hit, of course I'd be interested. I really enjoyed making it."
We should also expect James McAvoy, Michael Fassbender, Rose Byrne, January Jones and Jennifer Lawrence to return as well.
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